12 Regional Sandwiches That Belong On Every Food List

Every region in America has a sandwich that tells its story better than any slogan could. These twelve aren’t just local favorites; they’re national treasures waiting for more recognition. From New Orleans to Nebraska, each one earns its spot on every serious food list out there.

Italian Beef Sandwich

Maddy Alewine/Them Bites

Chicago nailed the formula: thin-sliced beef, hot giardiniera, and bread soaked in its own juices. It’s messy, bold, and absolutely deserving of permanent menu space. Get the recipe here.

Detroit Coney Dog

Maddy Alewine/Them Bites

A chili dog with staying power. Detroit’s Coney Dog is built for everyone; from night-shift workers to diehard fans; because it never misses the mark. Get the recipe here.

Muffuletta Sandwich

Maddy Alewine/Them Bites

Only New Orleans could dream up something this loud and proud. With layers of salami, cheese, and olive salad, it’s a party you can hold with both hands. Get the recipe here.

Runza

Maddy Alewine/Them Bites

Nebraska’s best-kept secret combines beef, cabbage, and onions inside soft bread. It’s hearty, portable, and quietly undefeated. Get the recipe here.

Hot Brown Sandwich

Maddy Alewine/Them Bites

Louisville’s baked masterpiece was built for crowds and comfort alike. Turkey, bacon, and creamy Mornay sauce come together like a standing ovation in sandwich form. Get the recipe here.

Roast Pork Sandwich

Maddy Alewine/Them Bites

Philly’s quiet champion beats any flashy rival. Garlicky greens, provolone, and juicy pork deliver everything you could want from a serious sandwich. Get the recipe here.

Beef on Weck

Maddy Alewine/Them Bites

Buffalo’s kummelweck roll and horseradish-spiked roast beef are an unmatched duo. It’s local pride, crusted with salt and success. Get the recipe here.

Fried Pork Tenderloin Sandwich

Maddy Alewine/Them Bites

Indiana doesn’t exaggerate; their pork tenderloin is bigger than the bun, and that’s the whole point. It’s crispy proof that excess can be done right. Get the recipe here.

North Shore Beef

Maddy Alewine/Them Bites

Massachusetts’ roast beef sandwich doesn’t chase attention; it commands it. Rare beef, melted cheese, and BBQ sauce are all it takes to win the crowd. Get the recipe here.

Fish Fry Sandwich

Maddy Alewine/Them Bites

In Wisconsin, this crispy classic keeps Fridays sacred. Golden fish, tartar sauce, and a simple bun; that’s how tradition stays undefeated. Get the recipe here.

Hot Beef Sandwich

Maddy Alewine/Them Bites

Mashed potatoes, gravy, and roast beef on white bread; it’s Midwestern practicality at its peak. A sandwich-meets-meal that refuses to fade away. Get the recipe here.

Fried Chicken Biscuit

Maddy Alewine/Them Bites

Crispy chicken and buttery biscuits might sound simple, but the South made it art. It’s the kind of sandwich you measure others against. Get the recipe here.

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