15 Regional Sandwiches You’ve Probably Never Tried (But Should!)

America’s best sandwiches aren’t just in big cities—they’re hiding in hometown delis and roadside diners everywhere. These fifteen regional favorites might be new to you, but every one is worth seeking out for a taste of local pride.

Runza

Nebraska’s pocket sandwich with seasoned beef, cabbage, and onion baked inside soft bread. Warm, filling, and beloved in the Midwest.

Pueblo Slopper

Open-faced cheeseburger drenched in green chile sauce, eaten with a fork. Colorado’s spicy, saucy comfort food hero.

Loose Meat Sandwich

Crumbly, saucy ground beef on a bun. A Midwest classic you have to taste to understand its loyal following.

Liver Mush Sandwich

Fried slices of pork and liver mush on white bread with yellow mustard. A North Carolina favorite and pure breakfast comfort.

Cudighi Sandwich

Spicy sausage, red sauce, and melted cheese in a hoagie roll. Upper Peninsula of Michigan’s Italian-American treat.

Olive Burger

Michigan’s burger with green olive mayo. Tangy, salty, and unforgettable once you try it.

Polish Boy

Cleveland classic: sausage, fries, slaw, and barbecue sauce piled in a bun. Sweet, smoky, and loaded with personality.

Bobbie Sandwich

Turkey, stuffing, cranberry, and mayo on a roll. Delaware’s answer to Thanksgiving leftovers, year-round.

Fish Fry Sandwich

Fried fish, lettuce, and tartar sauce in a soft bun. Midwest fish fries wouldn’t be the same without it.

Pepperoni Rolls

Soft rolls baked with spicy pepperoni inside. West Virginia miners’ lunchbox hero—and an Appalachian classic to this day.

Sailor Sandwich

Pastrami, knockwurst, and Swiss cheese with mustard on rye. Richmond, Virginia’s one-of-a-kind, meaty creation.

Fried Bologna Sandwich

Thick-cut bologna fried until crisp, served hot on white bread. Simple, salty, and pure nostalgia in every bite.

Pork Chop Sandwich

Breaded pork chop, bone-in, inside sliced bread. Crunchy, juicy, and beloved in the Midwest.

St. Paul Sandwich

Egg foo young patty with lettuce and mayo between white bread. St. Louis’ creative spin on both Chinese and American classics.

Chicken Spiedie

Marinated grilled chicken in a sub roll. Binghamton, New York’s summer favorite, loaded with tangy flavor and grill marks.