12 American Sandwiches That Everyone Should Try Once

America’s sandwich culture is as diverse as its regions. These twelve sandwiches are must-tries for anyone who loves food. Each one tells a story about where it came from, making every bite a little journey.

North Shore Beef

Maddy Alewine/Them Bites

Thinly sliced roast beef stacked high in a soft onion roll, with warm jus and a swipe of mayo or barbecue sauce. A Massachusetts classic, tender, juicy, and deeply comforting.

Primanti Brothers Sandwich

Maddy Alewine/Them Bites

Pittsburgh’s best: grilled meat, crisp fries, crunchy slaw, and tomato stacked between thick slices of Italian bread. Messy, filling, and totally legendary.

Runza

Maddy Alewine/Them Bites

Nebraska’s secret: soft bread stuffed with seasoned beef, cabbage, and onion. Warm, filling, and surprisingly addictive, this is Midwest comfort through and through.

Muffuletta Sandwich

Maddy Alewine/Them Bites

New Orleans brings Italian meats, cheese, and briny olive salad together on a massive sesame loaf. Huge, hearty, and brimming with bold flavor in every bite.

Italian Beef Sandwich

Maddy Alewine/Them Bites

Chicago’s pride: thin-sliced beef soaked in savory jus, packed into a chewy roll, and topped with spicy giardiniera. Juicy, spicy, and unforgettable.

Jucy Lucy

Maddy Alewine/Them Bites

Minneapolis icon: a burger patty stuffed with molten cheese. The ooze in every bite makes it a must for any burger fan.

Fish Fry Sandwich

Maddy Alewine/Them Bites

Golden fried fish fillet with lettuce and tartar sauce in a soft bun. Coastal, crispy, and classic for Fridays or any day of the week.

Lobster Roll

Maddy Alewine/Them Bites

Sweet lobster meat lightly dressed and packed into a toasted split-top bun. A taste of New England summer no matter the season.

Steak Bomb

Maddy Alewine/Them Bites

Shaved steak, onions, peppers, mushrooms, and cheese jammed into a hoagie roll. Every bite explodes with savory flavor.

Pastrami Burger

Maddy Alewine/Them Bites

Utah’s best-kept secret: juicy burger loaded with hot pastrami and melty cheese. Salty, smoky, and satisfying.

Cuban Sandwich

Maddy Alewine/Them Bites

Pressed Cuban bread, roast pork, ham, Swiss, pickles, and mustard. Crunchy, tangy, and full of personality.

Sloppy Joe

Maddy Alewine/Them Bites

Saucy ground beef cooked in tomato sauce and spices, heaped on a soft bun. Childhood favorite, always a comfort classic.

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