11 East Coast Sandwiches That Need to Be On Your Radar

The East Coast has a rich sandwich history, offering a wide range of unique and flavorful options. From seafood specialties to hearty meat-stuffed creations, these 11 sandwiches capture the spirit of coastal cuisine and deserve a place on your must-try list.

Crab Cake Sandwich

A close-up of a crab cake sandwich with a golden brown bun, leafy lettuce, sliced green pepper, and a thick, seasoned patty on a wooden surface.
Maddy Alewine/Them Bites

Maryland’s crab cake sandwich features thick, crispy crab cakes nestled in a soft bun with lettuce, tomato, and a spread of tartar sauce. It’s a celebration of fresh seafood that highlights the Chesapeake Bay’s best.

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Chicken Spiedie

A close-up of a Chicken Spiedie sandwich on a wooden surface, filled with grilled chicken, lettuce, tomato slices, onions, and banana peppers in a soft hoagie roll.
Maddy Alewine/Them Bites

This Binghamton, New York classic stacks marinated grilled chicken on Italian bread, creating a sandwich bursting with tangy, grilled goodness. It’s a regional favorite that has earned a loyal following.

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Roast Pork Sandwich

philly roast pork sandwich
Maddy Alewine/Them Bites

Philadelphia’s roast pork sandwich features tender, slow-roasted pork piled on a crusty roll, often topped with sharp provolone and sautéed greens. It’s a perfect mix of savory and comforting flavors.

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Muffuletta Sandwich

muffuletta
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Originating in New Orleans, the muffuletta layers Italian cold cuts, cheese, and a tangy olive salad on a round sesame bread. It’s a hearty and flavorful sandwich with roots in immigrant culture.

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Italian Beef Sandwich

A hand holds an Italian Beef Sandwich filled with sliced beef, mozzarella cheese, pickled carrots, red peppers, and yellow pepper rings on a sub roll.
Maddy Alewine/Them Bites

Though from Chicago, the Italian beef is a staple on many East Coast menus. Thinly sliced seasoned beef soaked in au jus, served on an Italian roll, sometimes topped with peppers for extra kick.

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North Shore Beef

Two North Shore Beef sandwiches with thick slices of meat, melted cheese, onions, and barbecue sauce overflowing from sesame seed buns are served on a baking sheet.
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This Massachusetts favorite is a roast beef sandwich loaded with gravy and cheese. It’s a cozy, filling meal perfect for colder days on the coast.

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Jucy Lucy

A person holds a Juicy Lucy Burger cut in half, revealing melted cheese, lettuce, pickles, tomato, and ground beef between two golden buns. The filling is juicy and layered with fresh vegetables.
Maddy Alewine/Them Bites

A cheese-stuffed burger that originated in Minneapolis but has gained popularity across the East Coast. It’s a juicy, molten cheese experience packed between two burger patties.

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Turkey Reuben

A close-up of a Turkey Reuben toasted sandwich with melted cheese and sliced turkey on golden brown bread, resting on a wooden surface.
Maddy Alewine/Them Bites

A lighter take on the classic Reuben with turkey, sauerkraut, Swiss cheese, and Russian dressing on rye bread. It’s a perfect blend of tang and richness for sandwich lovers.

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Beef on Weck

A beef on weck from the side, so you can see the entire sandwich.
Maddy Alewine/Them Bites

Popular in Buffalo, this sandwich features thinly sliced roast beef on a kummelweck roll with horseradish and au jus. It’s simple but packed with bold flavors.

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Hot Brown Sandwich

A cast iron skillet with three pieces of chicken hot brown, topped with melted cheese and bacon, sits on a white cloth on a wooden surface.
Maddy Alewine/Them Bites

A Kentucky original, the Hot Brown layers turkey, bacon, and tomato under a creamy Mornay sauce, then broils until golden. It’s a rich, satisfying sandwich perfect for brunch or dinner.

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