11 Iconic American Sandwiches Everyone Should Know

Some sandwiches are more than food—they’re American landmarks. These eleven icons have earned their spot in lunch history, proving that the right bite can tell a story all by itself.

Turkey Reuben

Maddy Alewine/Them Bites

This lighter twist on the classic Reuben keeps all the personality. Layers of turkey, Swiss cheese, sauerkraut, and dressing on rye bread still bring big deli energy, just with a fresher touch.

Get the recipe here.

Italian Beef Sandwich

Maddy Alewine/Them Bites

Chicago’s Italian Beef is soaked in jus and dripping with pride. Thin-sliced roast beef and spicy giardiniera make this one a masterclass in controlled chaos.

Get the recipe here.

Hot Brown Sandwich

Maddy Alewine/Them Bites

Louisville’s open-faced Hot Brown turns turkey, bacon, and creamy Mornay sauce into pure comfort. It’s Southern hospitality in bubbling form.

Get the recipe here.

Muffuletta Sandwich

Maddy Alewine/Them Bites

New Orleans knows how to layer flavor and heritage. Meats, cheeses, and olive salad packed into Sicilian bread give this sandwich real swagger.

Get the recipe here.

Chopped Cheese

Maddy Alewine/Them Bites

New York City’s chopped cheese is fast, loud, and unapologetically local. Beef, cheese, and attitude wrapped in foil—it’s the soul of the corner store.

Get the recipe here.

Detroit Coney Dog

Maddy Alewine/Them Bites

Detroit turned the humble hot dog into a cultural icon. Chili, mustard, and onions form a combination that’s stood the test of time and thousands of napkins.

Get the recipe here.

Beef on Weck

Maddy Alewine/Them Bites

Buffalo’s Beef on Weck is simplicity perfected—roast beef, horseradish, and a salted kummelweck roll. It’s salty, juicy, and absolutely timeless.

Get the recipe here.

Fried Chicken Biscuit

Maddy Alewine/Them Bites

The Southern fried chicken biscuit owns breakfast and lunch alike. Buttery biscuit, crunchy chicken, and pure comfort in every crumb.

Get the recipe here.

Cuban Sandwich

Maddy Alewine/Them Bites

Miami’s Cuban sandwich is the definition of balance. Pressed bread, roasted pork, ham, pickles, and mustard—all in harmony and ready to crunch.

Get the recipe here.

Lobster Roll

Maddy Alewine/Them Bites

Maine’s lobster roll is fresh, buttery luxury in a split-top bun. It’s the taste of the ocean without needing to leave your seat.

Get the recipe here.

Hot Beef Sandwich

Maddy Alewine/Them Bites

The Midwestern hot beef sandwich doesn’t just fill you up—it warms you up. Roast beef, white bread, and rich gravy turn simple into essential.

Get the recipe here.

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