11 Midwest Sandwiches Built For Real Appetites

In the Midwest, sandwiches aren’t side dishes; they’re the main event. These eleven creations prove that heartland cooking is all about generous portions, bold comfort, and recipes built to feed real appetites.

Horseshoe Sandwich

Crinkle-cut French fries and a burger patty on a plate, topped with a generous drizzle of creamy yellow cheese sauce being poured from above—just like in a classic Horseshoe Sandwich Recipe.
Maddy Alewine/Them Bites

Born in Springfield, Illinois, the Horseshoe is part sandwich, part edible tower. Toast, meat, fries, and cheese sauce combine into a glorious fork-and-knife situation that’s pure Midwest indulgence.

Get the recipe here.

Loose Meat Sandwich

A Loose Meat Sandwich with toasted bread, ground beef, chopped onions, mustard, mayonnaise, and pickles sits on a wooden board beside a pile of diced raw onions.
Maddy Alewine/Them Bites

Iowa’s loose meat sandwich skips the patty but keeps the beef. Seasoned ground beef piled onto a bun with mustard and pickles; simple, messy, and beloved since the 1920s.

Get the recipe here.

Olive Burger

An Olive Burger featuring a juicy beef patty and grapes covered in white sauce is served on a wooden cutting board. A hand rests behind the burger, with extra grapes scattered nearby for a unique twist.
Maddy Alewine/Them Bites

Michigan’s olive burger ditches ketchup for a briny mayo-olive spread. It’s salty, creamy, and utterly unique; a sandwich that could only have been born in the Great Lakes State.

Get the recipe here.

Hot Beef Sandwich

A plate featuring a classic hot beef sandwich: two slices of bread piled with shredded roast beef and brown gravy, served with a scoop of mashed potatoes smothered in rich gravy.
Maddy Alewine/Them Bites

Layers of roast beef on white bread, smothered in gravy; this Midwestern classic is what comfort looks like after a long day. It’s the region’s unofficial hug in food form.

Get the recipe here.

Fried Pork Tenderloin Sandwich

A crispy Fried Pork Tenderloin Sandwich with lettuce, tomato, and a sesame seed bun, placed on a wooden board.
Maddy Alewine/Them Bites

Indiana’s fried pork tenderloin sandwich is all about excess. Breaded and fried until golden, the meat hangs over the bun like it’s showing off; and it’s earned the right.

Get the recipe here.

Jucy Lucy

A person holds a Juicy Lucy Burger cut in half, revealing melted cheese, lettuce, pickles, tomato, and ground beef between two golden buns. The filling is juicy and layered with fresh vegetables.
Maddy Alewine/Them Bites

Minneapolis made the burger better by hiding the cheese inside. The Jucy Lucy oozes molten cheddar with every bite, making it a staple that defines Minnesota pride.

Get the recipe here.

Chicago Dog

A hand sprinkles seasoning onto two Chicago-Style Hot Dogs topped with sliced tomatoes, pickles, and peppers on a white plate. A cutting board with tomatoes is visible in the background.
Maddy Alewine/Them Bites

All-beef hot dog, poppy seed bun, and a garden of toppings; Chicago’s famous dog proves that “dragged through the garden” is a lifestyle, not a garnish.

Get the recipe here.

Italian Beef Sandwich

A hand holds an Italian Beef Sandwich filled with sliced beef, mozzarella cheese, pickled carrots, red peppers, and yellow pepper rings on a sub roll.
Maddy Alewine/Them Bites

Thin-sliced beef dunked in au jus and loaded with giardiniera; Chicago’s Italian Beef is equal parts tradition and test of endurance. You’ll need extra napkins for this one.

Get the recipe here.

Cudighi Sandwich

A toasted Cudighi Sandwich with melted cheese, sautéed green and red bell peppers, and tomato sauce sits on a wooden board. Bowls of tomato sauce and bell peppers are beside the sandwich.
Maddy Alewine/Them Bites

Up in Michigan’s Upper Peninsula, the cudighi combines spiced Italian sausage with marinara and melted mozzarella. It’s hearty, regional, and best enjoyed with cold weather and cold beer.

Get the recipe here.

Detroit Coney Dog

A white bowl filled with freshly baked golden brown runza bread rolls sits on a white cloth on a dark wooden table.
Maddy Alewine/Them Bites

Detroit’s iconic chili dog balances savory beef chili with mustard and onions. It’s diner food royalty that’s been perfected over generations of counter service.

Get the recipe here.

Runza

Maddy Alewine/Them Bites

Nebraska’s Runza bakes ground beef, onions, and cabbage into pillowy bread. Portable, hearty, and old-school; it’s the Midwest’s best road trip companion.

Get the recipe here.

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