11 Sandwiches That Carry the Spirit of Regional America

Every region has its pride on a plate, and sandwiches tell those stories best. These 11 are living proof that local spirit is served between bread.

Italian Beef

A hand holds an Italian Beef Sandwich filled with sliced beef, mozzarella cheese, pickled carrots, red peppers, and yellow pepper rings on a sub roll.
Maddy Alewine / Them Bites

Chicago’s Italian beef is dripping with au jus, often topped with giardiniera. It’s messy, flavorful, and a badge of Midwest pride. Get the recipe here.

Hot Brown

A cast iron skillet with three pieces of chicken hot brown, topped with melted cheese and bacon, sits on a white cloth on a wooden surface.
Maddy Alewine/Them Bites

Louisville’s open-faced turkey sandwich with bacon and Mornay sauce is rich, indulgent, and unmistakably Kentucky. Get the recipe here.

North Shore Beef

Two North Shore Beef sandwiches with thick slices of meat, melted cheese, onions, and barbecue sauce overflowing from sesame seed buns are served on a baking sheet.
Maddy Alewine/Them Bites

Massachusetts’ roast beef “three-way” with cheese, mayo, and BBQ sauce is saucy, sloppy, and pure New England attitude. Get the recipe here.

Pastrami Burger

pastrami burger
Maddy Alewine/Them Bites

Utah’s pastrami burger blends deli tradition with drive-thru comfort. It’s one of those sandwiches that instantly tells you where you are. Get the recipe here.

Lobster Roll

Two lobster rolls filled with creamy lobster salad sit on a wooden cutting board next to a pile of potato chips, making this classic lobster roll meal perfect for seafood lovers.
Maddy Alewine/Them Bites

Maine’s lobster roll is cold lobster meat on a buttered bun. It’s simple, decadent, and tied directly to the coast of New England. Get the recipe here.

Pork Tenderloin Sandwich

A crispy Fried Pork Tenderloin Sandwich with lettuce, tomato, and a sesame seed bun, placed on a wooden board.
Maddy Alewine / Them Bites

Indiana’s breaded pork tenderloin, often far larger than its bun, is fried perfection and a slice of small town Midwest life. Get the recipe here.

Muffuletta

muffuletta
Maddy Alewine/Them Bites

New Orleans’ muffuletta combines olive salad with layers of meat and cheese. One sandwich feeds a crowd and represents Crescent City spirit. Get the recipe here.

Runza

A white bowl filled with freshly baked golden brown runza bread rolls sits on a white cloth on a dark wooden table.
Maddy Alewine/Them Bites

Nebraska’s runza, a stuffed bread pocket filled with beef and cabbage, is portable comfort baked into the heart of the Plains. Get the recipe here.

Grinder Sandwich

grinder sandwich
Maddy Alewine/Them Bites

Connecticut’s grinder is packed with deli meats, cheese, and veggies. It’s a sandwich that feels right at home in every corner deli. Get the recipe here.

Chicken Spiedie

A close-up of a Chicken Spiedie sandwich on a wooden surface, filled with grilled chicken, lettuce, tomato slices, onions, and banana peppers in a soft hoagie roll.
Maddy Alewine/Them Bites

Binghamton’s spiedie of marinated grilled chicken tucked in bread carries small town charm and upstate New York pride. Get the recipe here.

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