12 Regional Sandwiches You Need To Try At Least Once

Every corner of America has its own take on what belongs between bread. These twelve regional sandwiches show how geography, history, and attitude come together to define how we eat; and why we keep coming back for more.

Kalua Pork Sandwich

kalua pork sandwich
Maddy Alewine/Them Bites

From Hawaii, the Kalua Pork Sandwich brings slow-roasted smokiness straight from the islands. Tender, juicy, and just sweet enough, it’s pure backyard paradise between buns.

Get the recipe here.

Chopped Cheese

A Chopped Cheese Sandwich Recipe on a white plate, filled with shredded lettuce, sliced tomatoes, seasoned meat, and topped with mayonnaise, set against a plain white background.
Maddy Alewine/Them Bites

Born on the griddles of New York City bodegas, the chopped cheese is fast, loud, and legendary. Ground beef, melted cheese, lettuce, and tomato make it the city’s unofficial handshake.

Get the recipe here.

Chicago Dog

A hand sprinkles seasoning onto two Chicago-Style Hot Dogs topped with sliced tomatoes, pickles, and peppers on a white plate. A cutting board with tomatoes is visible in the background.
Maddy Alewine/Them Bites

Chicago’s favorite hot dog is a rulebook on a bun. Mustard only, never ketchup, with a pile of sport peppers, tomatoes, and that unmistakable neon relish.

Get the recipe here.

North Shore Beef

Two North Shore Beef sandwiches with thick slices of meat, melted cheese, onions, and barbecue sauce overflowing from sesame seed buns are served on a baking sheet.
Maddy Alewine/Them Bites

Massachusetts’ North Shore beef sandwich is all about the “three-way”; mayo, cheese, and barbecue sauce. Served on a soft roll, it’s messy, rich, and completely New England.

Get the recipe here.

Hot Brown Sandwich

A cast iron skillet with three pieces of chicken hot brown, topped with melted cheese and bacon, sits on a white cloth on a wooden surface.
Maddy Alewine/Them Bites

From Louisville, Kentucky comes the Hot Brown, a bubbling open-faced sandwich of turkey, bacon, and creamy Mornay sauce. It’s indulgence that’s earned its reputation.

Get the recipe here.

Pueblo Slopper

slopper
Maddy Alewine/Them Bites

Colorado’s Pueblo Slopper is a cheeseburger drowned in green chile sauce. It’s equal parts sandwich and soup, and locals swear by its late-night healing powers.

Get the recipe here.

Olive Burger

An Olive Burger featuring a juicy beef patty and grapes covered in white sauce is served on a wooden cutting board. A hand rests behind the burger, with extra grapes scattered nearby for a unique twist.
Maddy Alewine/Them Bites

Michigan’s quirky olive burger turns salty olives and creamy mayo into a cult favorite topping. Once you’ve had one, you’ll wonder why anyone stopped at pickles.

Get the recipe here.

Runza

A white bowl filled with freshly baked golden brown runza bread rolls sits on a white cloth on a dark wooden table.
Maddy Alewine/Them Bites

Nebraska’s claim to fame stuffs ground beef, cabbage, and onions into soft bread dough. It’s hearty, portable, and feels like something your grandma would hand you with a smile.

Get the recipe here.

Sonoran Hot Dog

Sonoran dogs sitting on a cutting board, waiting to be eaten.
Maddy Alewine/Them Bites

In Tucson, the Sonoran Hot Dog is wrapped in bacon, loaded with beans, salsa, and jalapeños, then tucked in a fluffy bolillo roll. It’s Southwest comfort with style.

Get the recipe here.

Muffuletta Sandwich

A crispy chicken biscuit sandwich with mustard sits on a wooden surface, showcasing a golden, flaky biscuit and crunchy chicken fillet in this classic chicken biscuit delight.
Maddy Alewine/Them Bites

New Orleans doesn’t hold back. The muffuletta stacks cold cuts, cheese, and olive salad on round Sicilian bread; bold, briny, and built for sharing.

Get the recipe here.

Fried Pork Tenderloin Sandwich

Maddy Alewine/Them Bites

Indiana’s pork tenderloin sandwich is so oversized it looks like a joke until you take the first bite. Crispy, golden, and proud of it; it’s the heartland in sandwich form.

Get the recipe here.

Fried Chicken Biscuit

Maddy Alewine/Them Bites

Across the South, the fried chicken biscuit is both breakfast and redemption. Crunchy, buttery, and messy, it’s a bite that makes mornings worth showing up for.

Get the recipe here.

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