15 Sandwiches Every Serious Foodie Should Try

America is home to sandwiches that go beyond basic deli meat and cheese. These 15 sandwiches are essential for anyone serious about food. They showcase regional ingredients, special sauces, and unique combinations that food lovers crave.

Pepperoni rolls

pepperoni rolls out of the oven
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Originating from West Virginia, these soft rolls filled with pepperoni and melted cheese are a hearty snack or meal on their own. They’re portable and packed with taste.

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North shore beef

Two North Shore Beef sandwiches with thick slices of meat, melted cheese, onions, and barbecue sauce overflowing from sesame seed buns are served on a baking sheet.
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Thinly sliced beef with mayo, white American Cheese, and James River BBQ Sauce served over toast and topped with onions. This Massachusetts favorite combines comfort and flavor in every bite.

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Chicken fried steak sandwich

chicken fried steak
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A Texas specialty with crispy breaded steak fried to golden perfection, layered on a bun with creamy gravy. This sandwich turns comfort food into a handheld delight.

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Vermonter sandwich

A stacked Vermonter Sandwich breakfast with scrambled eggs and sliced turkey or ham between two pieces of toasted rustic bread, sitting on a wooden cutting board.
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Roast turkey with cheddar cheese and apples on hearty bread. This Vermont favorite balances savory and sweet with a satisfying crunch in every bite.

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Olive burger

An Olive Burger featuring a juicy beef patty and grapes covered in white sauce is served on a wooden cutting board. A hand rests behind the burger, with extra grapes scattered nearby for a unique twist.
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Ground beef mixed with olives, giving the burger a unique briny kick. This Michigan creation stands out with bold ingredients and rich, juicy meat.

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Crab melt

An upclose shot of a crab meat sandwich melt.
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Maryland’s classic with thick crab cakes, melted cheese, and toasted bread. It’s a seafood lover’s dream packed into a sandwich.

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Beef on Weck

A beef on weck from the side, so you can see the entire sandwich.
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A Buffalo, New York specialty featuring rare roast beef on a kummelweck roll with horseradish and pickles. This sandwich offers a tangy and spicy profile in every bite.

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Runza

A white bowl filled with freshly baked golden brown runza bread rolls sits on a white cloth on a dark wooden table.
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A Nebraska favorite consisting of seasoned ground beef and cabbage baked inside a soft bread pocket. It’s a handheld pie with hearty Midwestern roots.

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Crab cake sandwich

A close-up of a crab cake sandwich with a golden brown bun, leafy lettuce, sliced green pepper, and a thick, seasoned patty on a wooden surface.
Maddy Alewine/Them Bites

Another Maryland classic, featuring crisp crab cakes with lettuce and tartar sauce on a bun. It’s a seafood sandwich that delivers bright and fresh flavors.

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Patty melt

A close-up of a banh mi sandwich on a wooden board, packed with grilled meat, cilantro, sliced cucumber, pickled vegetables, and fresh herbs layered inside a crispy banh mi baguette.
Maddy Alewine/Them Bites

A grilled sandwich with ground beef, caramelized onions, and melted cheese on rye bread. It’s a satisfying meal with a perfect balance of textures.

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Banh mi

Maddy Alewine/Them Bites

A Vietnamese classic combining pickled vegetables, fresh herbs, and savory meat on a crunchy baguette. It’s an explosion of textures and tastes that food lovers crave.

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