15 Sandwiches That Prove the Midwest Does Food Right

The Midwest is home to some of the most satisfying and hearty sandwiches in the country. These 15 selections show that Midwestern sandwiches are about bold ingredients, unique combinations, and plenty of comfort. Whether it’s a hot beef sandwich or a loaded Italian beef, these sandwiches represent the best of the region’s rich food culture.

Detroit Coney Dog

Maddy Alewine/Them Bites

The Detroit Coney Dog is a flavorful hot dog topped with a special beef chili, mustard, and diced onions. This Michigan classic has a cult following and perfectly balances spice and tang in every bite.

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Loose Meat Sandwich

Maddy Alewine/Them Bites

Originating in Iowa, this sandwich features seasoned ground beef cooked loose rather than formed into a patty, served on a soft bun with pickles and onions. It’s a simple but deeply satisfying Midwestern staple.

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Jucy Lucy

Maddy Alewine/Them Bites

This Minneapolis invention is a cheeseburger with molten cheese tucked inside the patty instead of melted on top. It creates a juicy and delicious surprise in every bite that has fans coming back for more.

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Olive Burger

Maddy Alewine/Them Bites

This Michigan classic stands out by mixing chopped green olives right into the beef patty. The result is a salty and tangy twist on a burger that Midwest diners have loved for decades.

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Cudighi Sandwich

Maddy Alewine/Them Bites

This Upper Peninsula Michigan sandwich features a spicy Italian sausage patty on a hoagie roll, often topped with onions and peppers. It’s a regional favorite that offers bold spice and plenty of heartiness.

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North Shore Beef

Maddy Alewine/Them Bites

Hailing from Massachusetts but loved by Midwesterners who appreciate a good roast beef, this sandwich layers thinly sliced roast beef on a fresh bun and often includes cheese and au jus for dipping.

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Patty Melt

Maddy Alewine/Them Bites

The patty melt blends a juicy burger patty with melted cheese and sautéed onions, all sandwiched between grilled rye bread. It’s a diner classic found throughout the Midwest with timeless appeal.

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Runza

Maddy Alewine/Them Bites

A beloved Nebraska specialty, the Runza is a yeast bread pocket filled with seasoned ground beef, onions, and cabbage. It’s a portable, hearty sandwich that’s perfect for a filling lunch.

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Chicago Dog

Maddy Alewine/Them Bites

The Chicago Dog is a hot dog piled high with mustard, onions, relish, tomatoes, pickles, peppers, and celery salt. Its vibrant mix of toppings makes it one of the Midwest’s most iconic street foods.

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Italian Beef Sandwich

Maddy Alewine/Them Bites

This Chicago staple features thinly sliced roast beef soaked in au jus and piled onto a French roll, often topped with giardiniera or sweet peppers. It’s a messy, delicious experience worth seeking out.

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Beef on Weck

Maddy Alewine/Them Bites

A Buffalo, New York specialty popular in the Midwest, this sandwich features roast beef on a kummelweck roll, topped with horseradish and au jus. It’s a savory and satisfying choice for beef lovers.

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Chicken Spiedie

Maddy Alewine/Them Bites

Popular in Binghamton, New York, but loved across the Midwest, the chicken spiedie is marinated grilled chicken served on Italian bread with onions and peppers. It’s a fresh and flavorful alternative to traditional sandwiches.

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Turkey Reuben

Maddy Alewine/Them Bites

A lighter take on the classic Reuben, this sandwich uses turkey instead of corned beef, layered with Swiss cheese, sauerkraut, and Russian dressing on rye bread. It’s a well-balanced favorite across the Midwest.

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