9 Midwest Sandwiches Worth A Detour

The Midwest doesn’t brag; it just makes incredible sandwiches. These nine regional creations are reason enough to plan a detour. Whether it’s beef, breaded pork, or something you’ve never heard of, the heartland knows how to build a meal worth driving for.

Horseshoe Sandwich

Crinkle-cut French fries and a burger patty on a plate, topped with a generous drizzle of creamy yellow cheese sauce being poured from above—just like in a classic Horseshoe Sandwich Recipe.
Maddy Alewine/Them Bites

Springfield, Illinois takes “open-faced” to the extreme with layers of toast, hamburger patties, fries, and a river of cheese sauce. It’s bold, unapologetic, and engineered for comfort.

Get the recipe here.

Olive Burger

An Olive Burger featuring a juicy beef patty and grapes covered in white sauce is served on a wooden cutting board. A hand rests behind the burger, with extra grapes scattered nearby for a unique twist.
Maddy Alewine/Them Bites

Michigan’s quirky burger swaps ketchup for a briny olive and mayo mix. It’s tangy, creamy, and the perfect reminder that the Midwest never shies away from personality.

Get the recipe here.

Cudighi Sandwich

A toasted Cudighi Sandwich with melted cheese, sautéed green and red bell peppers, and tomato sauce sits on a wooden board. Bowls of tomato sauce and bell peppers are beside the sandwich.
Maddy Alewine/Them Bites

In Michigan’s Upper Peninsula, this spicy sausage sandwich reigns supreme. Served on a long roll with marinara and mozzarella, it’s a Yooper legend that deserves more fame.

Get the recipe here.

Loose Meat Sandwich

A Loose Meat Sandwich with toasted bread, ground beef, chopped onions, mustard, mayonnaise, and pickles sits on a wooden board beside a pile of diced raw onions.
Maddy Alewine/Them Bites

Iowa’s signature sandwich keeps it humble; crumbled beef, onions, and a soft bun. It’s messy in the best way and perfect proof that simplicity wins every time.

Get the recipe here.

Runza

A white bowl filled with freshly baked golden brown runza bread rolls sits on a white cloth on a dark wooden table.
Maddy Alewine/Them Bites

This Nebraska staple tucks seasoned beef and cabbage into pillowy bread. A hearty pocket of warmth that’s made to travel; and even better when eaten roadside.

Get the recipe here.

Jucy Lucy

A person holds a Juicy Lucy Burger cut in half, revealing melted cheese, lettuce, pickles, tomato, and ground beef between two golden buns. The filling is juicy and layered with fresh vegetables.
Maddy Alewine/Them Bites

Minneapolis perfected the surprise burger: a molten core of cheese hidden inside the patty. It’s a bite that burns your mouth and earns your respect in equal measure.

Get the recipe here.

Hot Beef Sandwich

A plate featuring a classic hot beef sandwich: two slices of bread piled with shredded roast beef and brown gravy, served with a scoop of mashed potatoes smothered in rich gravy.
Maddy Alewine/Them Bites

Served across Minnesota and the Dakotas, this open-faced favorite drenches roast beef and mashed potatoes in gravy. It’s stick-to-your-ribs Midwest tradition at its best.

Get the recipe here.

Polish Boy

A close-up of a hot dog in a bun topped with coleslaw, French fries, and drizzled with barbecue sauce—a classic worth adding to any list of 13 Working-Class Sandwiches That Don’t Mess Around, with extra fries scattered on the brown surface nearby.
Maddy Alewine/Them Bites

Cleveland’s masterpiece stacks kielbasa, fries, slaw, and barbecue sauce into one heroic sandwich. It’s sweet, smoky, and worth every napkin you’ll need.

Get the recipe here.

Fried Pork Tenderloin Sandwich

A crispy Fried Pork Tenderloin Sandwich with lettuce, tomato, and a sesame seed bun, placed on a wooden board.
Maddy Alewine/Them Bites

Indiana’s favorite sandwich is bigger than the bun; literally. Breaded, fried, and served with pickles and mustard, it’s pure Midwestern pride in golden-brown form.

Get the recipe here.

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