12 Iconic Sandwiches You Need to Experience

For every American road trip bucket list, these 12 sandwiches belong at the very top. Each one is a legend in its own right, representing its region with every bite. Don’t just read about them; go eat them.

Chicken Fried Steak Sandwich

chicken fried steak
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Texas-sized fried steak, golden and crunchy, tucked into a bun with tangy pickles and mayo. Comfort food squared. Get the Chicken Fried Steak Sandwich recipe

Primanti Brothers Sandwich

A Primanti Brothers Sandwich on thick white bread is filled with tomato slices, coleslaw, French fries, melted cheese, and grilled meat, all stacked high on a wooden cutting board.
Maddy Alewine/Them Bites

Pittsburgh’s king of carbs; thick bread, grilled meat, slaw, tomato, and a layer of fries all jammed together. Get the Primanti Brothers Sandwich recipe

Muffuletta Sandwich

muffuletta
Maddy Alewine/Them Bites

New Orleans stacks the meats, cheeses, and olive salad on a gigantic sesame roll. Salty, briny, and unforgettable. Get the Muffuletta Sandwich recipe

Pit Beef

A person holds a sandwich cut in half, revealing layers of pastrami, sliced onions, and creamy sauce between two slices of golden bread—a hearty creation inspired by a classic Pit Beef Recipe—resting above a wooden cutting board.
Maddy Alewine/Them Bites

Baltimore’s smokiest export; beef grilled over charcoal, thinly sliced and heaped on a Kaiser roll. Get the Pit Beef recipe

Turkey Reuben

A close-up of a Turkey Reuben toasted sandwich with melted cheese and sliced turkey on golden brown bread, resting on a wooden surface.
Maddy Alewine/Them Bites

Grilled rye loaded with turkey, Swiss, tangy kraut, and Russian dressing. A lighter but equally craveable spin on the classic. Get the Turkey Reuben recipe

Crab Cake Sandwich

A close-up of a crab cake sandwich with a golden brown bun, leafy lettuce, sliced green pepper, and a thick, seasoned patty on a wooden surface.
Maddy Alewine/Them Bites

Maryland blue crab, lightly fried and loaded into a soft bun. As fresh as the Chesapeake Bay breeze. Get the Crab Cake Sandwich recipe

Patty Melt

patty melt
Maddy Alewine/Them Bites

Beef, Swiss, and caramelized onions between toasted rye. It’s a diner legend; always a good decision. Get the Patty Melt recipe

Sailor Sandwich

A hand holds a hearty Sailor Sandwich with two thick slices of sausage, layers of corned beef, melted cheese, and mustard between toasted bread. A knife and wooden cutting board are visible in the background.
Maddy Alewine/Them Bites

Richmond, Virginia’s masterpiece; pastrami, grilled knockwurst, and Swiss cheese, all on rye. Salty, smoky, and satisfying. Get the Sailor Sandwich recipe

Loose Meat Sandwich

A Loose Meat Sandwich with toasted bread, ground beef, chopped onions, mustard, mayonnaise, and pickles sits on a wooden board beside a pile of diced raw onions.
Maddy Alewine/Them Bites

Iowa’s simple classic; crumbled beef, onions, and a soft bun. It’s like a burger that lost its shape and found its calling. Get the Loose Meat Sandwich recipe

Fried Chicken Biscuit

pastrami burger
Maddy Alewine/Them Bites

Golden, crispy chicken on a buttery, tender biscuit. Southern mornings don’t get better than this. Get the Fried Chicken Biscuit recipe

Beef on Weck

Maddy Alewine/Them Bites

Buffalo’s signature: rare roast beef, sea salt, caraway, and horseradish on a kummelweck roll. Get the Beef on Weck recipe

Pastrami Burger

Maddy Alewine/Them Bites

Utah’s over-the-top creation; a grilled beef patty, loads of pastrami, and melted cheese on a bun. Get the Pastrami Burger recipe

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