13 Unstoppable Sandwiches You’ll Love in America

ByJD Alewine Published On Updated on

American sandwiches don’t quit, and these 13 unstoppable creations are proof. Every bite is bold, inventive, and impossible to forget.

Primanti Brothers Sandwich

A Primanti Brothers Sandwich on thick white bread is filled with tomato slices, coleslaw, French fries, melted cheese, and grilled meat, all stacked high on a wooden cutting board.
Maddy Alewine/Them Bites

Pittsburgh stacks fries, coleslaw, tomatoes, and your choice of meat on thick Italian bread. It’s more than a sandwich;it’s an event. Get Primanti Brothers Sandwich

Shrimp Po Boy

shrimp po boy
Maddy Alewine/Them Bites

Crispy shrimp, French bread, and spicy remoulade combine for a po boy that defines New Orleans. The crunch is legendary. Try Shrimp Po Boy

Cuban Sandwich

A close-up of two hands holding a halved Cubano, showing layers of roast pork, ham, Swiss cheese, pickles, and mustard between toasted bread.
Maddy Alewine/Them Bites

Pressed Cuban bread holds roast pork, ham, Swiss cheese, pickles, and mustard in one perfect package. Miami wouldn’t be the same without it. Order Cuban Sandwich

Pueblo Slopper

slopper
Maddy Alewine/Them Bites

This Colorado creation is a cheeseburger smothered in green chile and onions, served open-faced. Bring a fork, and maybe a bib. Try Pueblo Slopper

Fried Chicken Biscuit

A crispy chicken biscuit sandwich with mustard sits on a wooden surface, showcasing a golden, flaky biscuit and crunchy chicken fillet in this classic chicken biscuit delight.
Maddy Alewine/Them Bites

Fried chicken inside a buttery biscuit is Southern comfort at its peak. This one’s irresistible for breakfast, lunch, or late-night snacks. Order Fried Chicken Biscuit

Turkey Reuben

A close-up of a Turkey Reuben toasted sandwich with melted cheese and sliced turkey on golden brown bread, resting on a wooden surface.
Maddy Alewine/Them Bites

The turkey reuben swaps out corned beef for turkey but keeps the Swiss, sauerkraut, and Russian dressing on grilled rye. It’s lighter, but just as craveable. Get Turkey Reuben

North Shore Beef

Two North Shore Beef sandwiches with thick slices of meat, melted cheese, onions, and barbecue sauce overflowing from sesame seed buns are served on a baking sheet.
Maddy Alewine/Them Bites

Roast beef, mayo, white American cheese, and James River BBQ sauce fill a soft roll. Massachusetts’ three-way is pure sandwich perfection. Try North Shore Beef

Runza

A white bowl filled with freshly baked golden brown runza bread rolls sits on a white cloth on a dark wooden table.
Maddy Alewine/Them Bites

Nebraska’s runza is a baked bread pocket filled with seasoned beef and cabbage. Portable, hearty, and pure Midwest comfort. Order Runza Sandwich

Steamed Burger

A close-up of a steamed burger with lettuce, tomato, onion, melted cheese, and a beef patty on a bun, placed on a wooden surface.
Maddy Alewine/Them Bites

Connecticut’s steamed burger is super juicy and topped with gooey cheese. It’s a one-of-a-kind burger experience. Get Steamed Burger

Bobbie Sandwich

patty melt
Maddy Alewine/Them Bites

Turkey, stuffing, cranberry sauce, and mayo make this Delaware legend taste like Thanksgiving in every bite. It’s holiday spirit on a hoagie. Order Bobbie Sandwich

Beef on Weck

Maddy Alewine/Them Bites

Buffalo’s beef on weck features juicy roast beef, horseradish, and a salty kummelweck roll. It’s a classic you’ll crave again and again. Try Beef on Weck

Patty Melt

Maddy Alewine/Them Bites

This old-school favorite mixes grilled onions, beef, and Swiss cheese on rye. It’s a gooey, crispy, griddled masterpiece. Order Patty Melt

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