13 Epic Regional Sandwiches America Should Treasure

America’s regions each carry their own sandwich pride, and these 13 epic picks show just how creative and comforting they can be. From coast to coast, these are the treasures worth celebrating.

Liverwurst Sandwich

Maddy Alewine/Them Bites

This classic cold-cut sandwich layers slices of liverwurst with mustard, onions, and rye bread. Old-school and satisfying, it remains a lunchtime favorite across America. Get the recipe here.

Albuquerque Turkey Sandwich

Maddy Alewine/Them Bites

From New Mexico, this turkey sandwich gets a Southwestern kick with green chile, cheese, and hearty bread. It’s warm, melty, and just the right amount of spicy. Get the recipe here.

Italian Beef Sandwich

Maddy Alewine/Them Bites

Chicagoans line up for this pile of thinly sliced beef dipped in au jus and topped with giardiniera on a long roll. Juicy and bold, it’s Windy City tradition. Get the recipe here.

Kalua Pork Sandwich

Maddy Alewine/Them Bites

From Hawaii, this sandwich uses slow-cooked shredded pork infused with smoky island flavor. Served on a bun, it’s tender, juicy, and unforgettable. Get the recipe here.

Primanti Brothers Sandwich

Maddy Alewine/Them Bites

Pittsburgh’s claim to fame stacks meat, cheese, coleslaw, and fries right between thick slices of Italian bread. It’s hearty, filling, and pure Steel City spirit. Get the recipe here.

Bobbie Sandwich

Maddy Alewine/Them Bites

Known as the “Thanksgiving sandwich,” this Delaware classic piles turkey, stuffing, and cranberry sauce onto a sub roll. Every bite tastes like the holidays. Get the recipe here.

Sailor Sandwich

Maddy Alewine/Them Bites

Richmond, Virginia delivers rye bread stuffed with pastrami, knockwurst, and Swiss cheese. It’s smoky, tangy, and a serious bite of Southern deli tradition. Get the recipe here.

Grinder Sandwich

Maddy Alewine/Them Bites

Connecticut’s go-to sub, the grinder, can be filled with cold cuts, cheese, and crisp veggies. Customizable and reliable, it’s the Northeast’s answer to a perfect lunch. Get the recipe here.

Bison Burger

Maddy Alewine/Them Bites

Wyoming serves up bison burgers that are lean, juicy, and deeply satisfying. Set on a bun with classic toppings, it’s a true taste of the American West. Get the recipe here.

Pueblo Slopper

Maddy Alewine/Them Bites

Pueblo, Colorado piles an open-faced burger with green chile and onions, then smothers it in sauce. It’s messy, spicy, and unforgettable. Get the recipe here.

Hot Beef Sandwich

Maddy Alewine/Them Bites

From Minnesota, this diner classic features roast beef and gravy over bread, served with mashed potatoes. It’s hearty, warm, and built for cold winters. Get the recipe here.

Cuban Sandwich

Maddy Alewine/Them Bites

Miami’s Cuban sandwich layers ham, roast pork, Swiss cheese, pickles, and mustard on Cuban bread, pressed until crisp. It’s bold and packed with tradition. Get the recipe here.

Steak Bomb

Maddy Alewine/Them Bites

New England’s steak bomb loads a hoagie roll with shaved steak, peppers, onions, mushrooms, and melted provolone. It’s as over-the-top as its name suggests. Get the recipe here.

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