13 Monumental Sandwiches to Eat Across America

From coast to coast, these monumental sandwiches prove that America’s best bites are handheld. Dig into these 13 picks and start plotting your next foodie road trip.

Loose Meat Sandwich

A Loose Meat Sandwich with toasted bread, ground beef, chopped onions, mustard, mayonnaise, and pickles sits on a wooden board beside a pile of diced raw onions.
Maddy Alewine/Them Bites

Iowa’s loose meat sandwich skips the patty for perfectly seasoned ground beef piled onto a soft bun. Sometimes, less structure means more comfort. get recipe here

Muffuletta Sandwich

muffuletta
Maddy Alewine/Them Bites

New Orleans’ muffuletta piles Italian meats, cheese, and tangy olive salad onto sesame bread. Every bite is a trip to the French Quarter. get recipe here

Beef on Weck

A beef on weck from the side, so you can see the entire sandwich.
Maddy Alewine/Them Bites

This Buffalo classic is all about tender roast beef on a kummelweck roll with a kick of horseradish. Simplicity at its best, with a roll that steals the show. get recipe here

Chicken Bacon Ranch Sliders

Nine Chicken Bacon Ranch Sliders on a baking sheet, with one slider separated from the group. The buns are golden brown and slightly shiny, with savory filling visible around the edges.
Maddy Alewine/Them Bites

Bite-sized buns stuffed with chicken, bacon, and creamy ranch are the party sandwich you didn’t know you needed. One is never enough, trust us. get recipe here

Detroit Coney Dog

A person holds a chili dog topped with chopped onions and mustard—an Easy Detroit Coney Dog Recipe—while another chili dog and scattered onions rest on a wooden surface.
Maddy Alewine/Them Bites

A snappy hot dog topped with meaty chili, onions, and mustard, Detroit’s Coney is a legend. It’s a street food icon with a dedicated fanbase. get recipe here

Pastrami Burger

pastrami burger
Maddy Alewine/Them Bites

This Utah invention tops a burger with a generous pile of pastrami for a one-two punch of beef. It’s as bold as it sounds, and just as addictive. get recipe here

North Shore Beef

Two North Shore Beef sandwiches with thick slices of meat, melted cheese, onions, and barbecue sauce overflowing from sesame seed buns are served on a baking sheet.
Maddy Alewine/Them Bites

Roast beef, mayo, American cheese, and James River BBQ sauce;this Massachusetts favorite is a rite of passage. It’s the ultimate three-way sandwich, built for big appetites. get recipe here

Chicken Spiedie

A close-up of a Chicken Spiedie sandwich on a wooden surface, filled with grilled chicken, lettuce, tomato slices, onions, and banana peppers in a soft hoagie roll.
Maddy Alewine/Them Bites

Chunks of marinated chicken grilled and tucked into soft Italian bread. The spiedie is Binghamton’s best-kept secret. get recipe here

Primanti Brothers Sandwich

A Primanti Brothers Sandwich on thick white bread is filled with tomato slices, coleslaw, French fries, melted cheese, and grilled meat, all stacked high on a wooden cutting board.
Maddy Alewine/Them Bites

Pittsburgh’s hero comes stacked with meat, fries, slaw, and tomato between slices of thick Italian bread. It’s a whole meal disguised as a sandwich. get recipe here

Steak Bomb

Two lobster rolls filled with creamy lobster salad sit on a wooden cutting board next to a pile of potato chips, making this classic lobster roll meal perfect for seafood lovers.
Maddy Alewine/Them Bites

Loaded with shaved steak, peppers, onions, mushrooms, and cheese, this New England classic lives up to its explosive name. Each bite packs in the good stuff. get recipe here

Polish Boy

Maddy Alewine/Them Bites

Kielbasa, fries, slaw, and barbecue sauce collide in Cleveland’s signature sandwich. This is a messy, meaty, must-try for sandwich fans. get recipe here

Vermonter Sandwich

Maddy Alewine/Them Bites

Apple, cheddar, and turkey or ham come together in a crusty Vermont roll. The combo of sweet and salty is pure New England. get recipe here

Lobster Roll

Maddy Alewine/Them Bites

Sweet lobster meat and a buttery roll make this Maine classic a summer staple. It’s a bucket list sandwich, no question. get recipe here

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